Obesity & Weight Loss Therapy

Type 2 Diabetes Mellitus (T2DM) is the most common and costly endocrine disease [1] which is associated with increased morbidity and premature death, especially from cardiovascular diseases, myocardial infarction and stroke [2]. The prevalence of T2DM has increased dramatically over the past two decades. According to the most recent survey, the number of people who are currently affected by this disease is 230 million worldwide and it is estimated that it rises to 370 million people by the year 2025 [3]. The prevalence of this disease in Iran was reported to be 7.7% in people younger than 65 years [4]. Blindness, renal failure, and amputation are of the most important long term complications of T2DM [5].